LymphedemaV1, Main, Exploration, bibRecord, 000761

Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature.

Identifieur interne : 000761 ( Main/Exploration ); précédent : 000760; suivant : 000762

Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature.

Auteurs : Aileen Grace P. Arriola [États-Unis] ; Laura A. Taylor [États-Unis] ; Eseosa Asemota [États-Unis] ; Markus D. Boos [États-Unis] ; David E. Elder [États-Unis] ; Kristy L. Weber [États-Unis] ; Robert G. Micheletti [États-Unis] ; Paul J. Zhang [États-Unis]

Source :

Journal of cutaneous pathology [ 1600-0560 ] ; 2017.

RBID : pubmed:27730656

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Femelle, Humains, Hémangioendothéliome (anatomopathologie), Lymphoedème (), Tumeurs cutanées (anatomopathologie), Tumeurs vasculaires (anatomopathologie).
MESH :
- anatomopathologie : Hémangioendothéliome, Tumeurs cutanées, Tumeurs vasculaires.
- Adulte d'âge moyen, Femelle, Humains, Lymphoedème.

English descriptors

KwdEn :
- Female, Hemangioendothelioma (pathology), Humans, Lymphedema (complications), Middle Aged, Skin Neoplasms (pathology), Vascular Neoplasms (pathology).
MESH :
- complications : Lymphedema.
- pathology : Hemangioendothelioma, Skin Neoplasms, Vascular Neoplasms.
- Female, Humans, Middle Aged.

Abstract

Retiform hemangioendothelioma (RH) is a rare vascular neoplasm with a high rate of local recurrence and low metastatic potential. We describe an unusual case of RH in a 45-year-old patient with Milroy disease, with a prominent solid component diffusely involving a chronic lymphedematous leg. This case is consistent with the postulated relationship between lymphedema and vascular neoplasms developing as a result of local immune dysfunction, and highlights the need to closely monitor patients with Milroy disease for pathologic changes. Our case highlights a unique example of RH with atypical features. There are several noteworthy unusual clinical and histologic findings including diffuse involvement of an entire limb, solid component with cytologic atypia, D2-40 expression, and first-time-reported association with Milroy disease. Given the atypical histologic presentation of cytologic atypia, solid areas and atypical immunohistochemical profile with D2-40 positivity, this case could cause diagnostic difficulty, especially in the setting of such a broad clinical differential.

DOI: 10.1111/cup.12844
PubMed: 27730656

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Retiform hemangioendothelioma (RH) is a rare vascular neoplasm with a high rate of local recurrence and low metastatic potential. We describe an unusual case of RH in a 45-year-old patient with Milroy disease, with a prominent solid component diffusely involving a chronic lymphedematous leg. This case is consistent with the postulated relationship between lymphedema and vascular neoplasms developing as a result of local immune dysfunction, and highlights the need to closely monitor patients with Milroy disease for pathologic changes. Our case highlights a unique example of RH with atypical features. There are several noteworthy unusual clinical and histologic findings including diffuse involvement of an entire limb, solid component with cytologic atypia, D2-40 expression, and first-time-reported association with Milroy disease. Given the atypical histologic presentation of cytologic atypia, solid areas and atypical immunohistochemical profile with D2-40 positivity, this case could cause diagnostic difficulty, especially in the setting of such a broad clinical differential.</div>
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<name sortKey="Asemota, Eseosa" sort="Asemota, Eseosa" uniqKey="Asemota E" first="Eseosa" last="Asemota">Eseosa Asemota</name>
<name sortKey="Boos, Markus D" sort="Boos, Markus D" uniqKey="Boos M" first="Markus D" last="Boos">Markus D. Boos</name>
<name sortKey="Elder, David E" sort="Elder, David E" uniqKey="Elder D" first="David E" last="Elder">David E. Elder</name>
<name sortKey="Micheletti, Robert G" sort="Micheletti, Robert G" uniqKey="Micheletti R" first="Robert G" last="Micheletti">Robert G. Micheletti</name>
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<name sortKey="Weber, Kristy L" sort="Weber, Kristy L" uniqKey="Weber K" first="Kristy L" last="Weber">Kristy L. Weber</name>
<name sortKey="Zhang, Paul J" sort="Zhang, Paul J" uniqKey="Zhang P" first="Paul J" last="Zhang">Paul J. Zhang</name>
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Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature.

Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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